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Chunk #10 — Results — Genetic relationship of OCD with other phenotypes

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Genome-wide analyses identify 30 loci associated with obsessive-compulsive disorder.
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Using phenome-wide association analysis, we examined whether the 30 independent OCD-associated loci identified by our GWAS meta-analysis have previously been associated with other phenotypes (see Supplementary Tables 17a–d for look-ups in four, partially overlapping GWAS-databanks and Table 1 for highlighted associations). We found that 22 of the 30 loci were associated with other phenotypes, including schizophrenia (seven loci), depression/major depressive disorder (two loci), bipolar disorder (one locus), neuroticism (seven loci), educational attainment (seven loci), and body fat mass or body mass index (eight loci).