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Chunk #17 — Results — Expressions influenced by genetic and risk factors are enriched in immunity and defense genes

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Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.
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An ontology analysis using the Panther system demonstrated that, by reference to the list of 12,808 genes expressed in monocytes, the set of 465 expression traits affected by multiple sources of variability was enriched in “Immunity and defense” genes (69 observed/35.8 expected, P = 4.5×10−6), especially in the sub-categories of “Macrophage-mediated immunity” (18/3.6, P = 7.5×10−6).