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Chunk #16 — Methods — ERP Methods — Subject preparation

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Novelty P3 reductions in depression: characterization using principal components analysis (PCA) of current source density (CSD) waveforms.
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A Lycra stretch electrode cap was used to record from a 66-channel, expanded 10–20 scalp montage (Pivik et al., 1993), with additional channels for nose (used as off-line reference) and bipolar eye activity (left [LE] and right [RE] outer canthi; above [TE] and below [BE] right eye) to monitor lateral eye movements and blinks. Cap placement was optimized by precise measurements of electrode locations with respect to landmarks of the 10–20 system (nasion, inion, auditory meatus, vertex). The scalp placements were prepared using a conventional water soluble electrolyte gel, and the electrode–scalp interface was verified by the acquisition software (ActiView; BioSemi, 2001). During acquisition, the active recording reference was composed of sites PO1 (common mode sense) and PO2 (driven right leg).