sequence, and (ii) overlapped the variable nucleotide(s) (thus changing the PWM score) were considered. Then, the change in log-odds (LOD) score was calculated. In cases where the weaker match was did not pass the less-stringent threshold, an approximate minimum change of LOD score was reported, corresponding to the difference between the score of the stronger match to the score required to pass the less-stringent threshold. In cases where both allelic variants surpassed the less-stringent threshold, the exact difference in score was reported.