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Chunk #7 — METHODS

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HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants.
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sequence, and (ii) overlapped the variable nucleotide(s) (thus changing the PWM score) were considered. Then, the change in log-odds (LOD) score was calculated. In cases where the weaker match was did not pass the less-stringent threshold, an approximate minimum change of LOD score was reported, corresponding to the difference between the score of the stronger match to the score required to pass the less-stringent threshold. In cases where both allelic variants surpassed the less-stringent threshold, the exact difference in score was reported.