Spit for Science is an ongoing longitudinal study of college students enrolled in a large, urban university in the Mid-Atlantic (Dick et al., 2014). Briefly, incoming students age 18 or older were eligible to complete phenotypic assessments, which covered a wide range of topics but focused on alcohol use. Study data were collected and managed using REDCap electronic data capture tools (Harris et al., 2009) hosted at Virginia Commonwealth University. Follow-up assessments were completed in subsequent spring semesters. Individuals who did not participate in the first wave of data collection (including those who turned 18 after the end of the first wave of data collection) had the opportunity to join the study the following spring; those who participated during their first year were eligible to complete follow-up assessments each spring. Participants who completed the phenotypic assessments were eligible to provide a DNA sample. The current study includes three cohorts, which matriculated in Fall 2011 (N=2,714), 2012 (N=2,486), and 2013 (N=2,403), for a total N=7,603. Ethical approval was obtained from the local Institutional Review Board.
