Chunk #8 — 3. Methods

Source: Molecular assays for characterization of alternatively spliced isoforms of the u opioid receptor (MOR).
Embedded: yes

Text

Mu-opioids signaling also involves production and release of NO via Ca2+-stimulated activation of constitutive nitric oxide synthase that has been specifically linked to MOR-3 isoform of OPRM1. (8) The following technique developed to rapidly evaluate MOR agonist NO stimulating activity in vitro.