An important strength of this study is that it focused on adults with current cannabis use disorders and nicotine dependence, in contrast to several studies that have examined individuals with past diagnoses of cannabis use disorders or nicotine dependence or who reported as few as one occasion of lifetime cannabis or tobacco use. The inclusion of individuals with current diagnoses provides confidence that results may have immediate relevance for individuals seeking treatment for cannabis and tobacco. Other strengths are the use of a nationally-representative sample; statistical adjustment for potential confounders of the association of co-occurring cannabis use disorders and nicotine dependence with correlates of interest, and examination of a wide variety of correlates that have implications for substance abuse treatment and public health.