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Chunk #64 — STAR★METHODS — METHOD DETAILS — Burden Analyses — Chi-square Analysis of Deviance

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De Novo Coding Variants Are Strongly Associated with Tourette Disorder.
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We utilized a chi-square analysis of deviance test to determine whether the mutation rates per bp differed between the TIC Genetics, the TSAICG, and the SSC Sibling trios. We first conducted a poisson regression with the glm function in R and then utilized the anova function to test the resulting model.