Chunk #38 — REGULATORY ELEMENTS IN THE UNTRANSLATED REGIONS — Genetic variants at the 3′UTR — RNA-binding proteins and 3′UTR regulation

Source

Genetic variants in mRNA untranslated regions.

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yes

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Genetic variants that modify the binding sites of RBPs in the 3′UTR can influence mRNA stability, translation efficiency and localization, by affecting the RNA-binding sequence and domain.