Chunk #51 — Materials and Methods — Meta-Analysis Gene-set Enrichment of variaNT Associations (MAGENTA) — Steps 2 and 3: Scoring genes based on SNP association scores and correcting for confounders
For each gene g in the genome we calculated a score, that is the probability that the gene is associated with a given disease or trait. In computing this score we corrected for the confounding effects of physical and genetic properties of genes on the gene p-value.