Since 2007, numerous robust and replicable genetic findings have been reported for psychiatric disorders. These advances have mostly been via genome-wide association (GWAS) and structural variation (SV) studies, although studies of uncommon or rare exonic variation are likely to play a prominent role in the next few years. These results meet community standards in human genetics for significance and replication. 6 Although these findings often appeared in high-profile journals, sentiments like “genetics has failed in psychiatry” or “there are no genes for psychiatric disorders” are still heard. A review of psychiatric genetics is thus particularly opportune.
