the duration of ethanol consumption in mouse models of excessive drinking (Osterndorff-Kahanek et al., 2015). Furthermore, inclusion criteria should account for variables such as age, ethnicity, developmental disorders, history of other psychiatric or neurological disorders, and other degenerative diseases. Minimizing confounding variables is essential to uncover the biologically relevant alcohol-responsive gene networks in humans that may underlie the specific pathophysiology of AUD.
