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Chunk #12 — MATERIALS AND METHODS — Weighted genome coexpression network analysis

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Antenatal prediction of postpartum depression with blood DNA methylation biomarkers.
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Weighted genome co-expression network analysis (WGCNA)21 was performed using the WGCNA package in R. In the mouse comparisons, 3606 mean DMR values were used with a power of 20 and minimum module size of 10. For all human analyses, 13 091 nominally significant loci in the combined comparison of PPD (N=11) to non-PPD (N=21) euthymic cohort women were used for correlation with a power of 10 and minimum module size of 10.