The eyes open condition was an independent replication of the eyes closed condition because the eye conditions were recorded at different times and the order of recording was counter balanced across subjects. Multivariate analysis of variance (MANOVA) with Bonferroni correction was performed where eyes open and eyes closed conditions and left vs. right hemisphere as factors for all 91 Brodmann area combinations. The MANOVA was used because it controls for the intercorrelation between the dependent and between the independent variables. Table 4 shows the results of these analyses which showed that eyes open vs. eyes closed conditions were not statistically significantly different in the x, y, z directions and resultant vector for phase shift duration. However, eyes open vs. closed conditions were statistically significant for phase lock duration in the x and z directions and for the resultant vector. In all cases, phase lock duration in the eyes closed condition was longer than in the eyes open condition (mean difference = 9.52 ms).