SCZ-PRS have primarily been applied to understand relationships across 6 broad domains: schizophrenia-related phenotypes (e.g., psychosis, treatment), other psychiatric disorders, cognition, brain-related phenotypes, immune and health-related and, finally, other phenotypes (e.g., urbancity). Effect sizes for these studies are graphically summarized in Figure 2 with individual study summaries provided in Table 1–6, and discussed (briefly) below.