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Chunk #37 — PRS Application: The example of Schizophrenia

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Polygenic Risk Scores in Clinical Psychology: Bridging Genomic Risk to Individual Differences.
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SCZ-PRS have primarily been applied to understand relationships across 6 broad domains: schizophrenia-related phenotypes (e.g., psychosis, treatment), other psychiatric disorders, cognition, brain-related phenotypes, immune and health-related and, finally, other phenotypes (e.g., urbancity). Effect sizes for these studies are graphically summarized in Figure 2 with individual study summaries provided in Table 1–6, and discussed (briefly) below.