We applied PolyFun + SuSiE to fine-map 49 traits in the UK Biobank, including 33 traits analyzed in refs. 30,31, 9 blood cell traits analyzed in ref. 12, and 7 metabolic traits (average N=318K; Supplementary Table 8). For each trait we fine-mapped up to 2,763 overlapping 3Mb loci spanning M=18,212,157 imputed MAF≥0.001 SNPs with INFO score≥0.6 (including short indels; excluding three long-range LD regions and loci with close to zero heritability; Methods). We assigned to each SNP its PIP computed using the locus in which it was most central. We have publicly released the PIPs and the prior and posterior means and variances of the causal effect sizes for all SNPs and traits analyzed.
