Our findings regarding conduct disorder are more difficult to interpret. Conduct disorder is a serious, fairly common childhood and adolescent disorder (Nock et al., 2006). Although evidence-based treatments do exist (Henggeler et al., 2002), some follow up studies of adolescents in treatment suggest a high persistence of antisocial and substance use behaviors (Myers et al., 1998). Currently, no medications are FDA-approved to treat this disorder. Genetic association studies provide one possible avenue to better delineate its etiology and neurobiological basis. The recent finding of an association between the rs279871 SNP in the GABRA2 gene and conduct disorder is therefore, of high interest.
