Given the observed delay in transition from alcohol initiation to onset of AD symptoms and AD diagnosis associated with parental separation in the fully adjusted models, we conducted a series of subsidiary analyses. Simple logistic regression analyses predicting the development of AD symptoms and AD diagnosis from parental separation without any other predictors indicated that parental separation was associated with significantly increased lifetime risk of having at least one DSM-IV AD symptom (OR=1.34 [95% CI: 1.05–1.70] and a somewhat increased lifetime risk of DSM-IV AD (OR=1.17 [0.85–1.63]).
