Next, we examined the expression of Zfhx1b's closely related homologue, Zfhx1a, in the E12.5 control and mutant telencephalon. Both Zfhx1a and Zfhx1b are expressed in the subpallial VZ, whereas only Zfhx1b is clearly expressed in the SVZ (Figures 1A and S1B). Zfhx1a's expression did not clearly change in the Nkx2.1-Cre mediated Zfhx1b mutant (Figure S1B-S1D’). Thus, in the Nkx2.1-Cre conditional Zfhx1b mutant, only the VZ of the MGE continued to strongly express a Zfhx homologue.
