Subsequently, a meta-analysis evaluated 26 RP treatment outcome studies totaling 9,504 participants [36]. The authors examined two primary outcomes (substance use and psychosocial functioning) and several treatment moderators. Effect sizes indicated that RP was generally successful in reducing substance use (r = .14) and improving psychosocial functioning (r = .48), consistent with its purpose as both a specific and global intervention approach. Moderation analyses suggested that RP was consistently efficacious across treatment modalities (individual vs. group) and settings (inpatient vs. outpatient). RP was most effective for reducing alcohol and polysubstance use and less effective for tobacco and cocaine use--a contrast to Carroll's [35] finding of comparable efficacy across drug classes. In addition, RP was more effective when delivered in conjunction with pharmacotherapy, when compared to wait-list (vs. active) comparison conditions, and when outcomes were assessed soon after treatment. Though some findings were considered tentative due to sample sizes, the authors concluded that RP was broadly efficacious [36].