Finnish Caucasians are regarded as a population isolate. The sample from Helsinki, Finland, has been described in detail elsewhere ( Lappalainen et al, 1998). In total, 547 men were genotyped: 266 alcoholics and 281 non-alcoholics. The sample was comprised of: 173 incarcerated alcoholic criminal offenders, 159 relatives (93 alcoholic, 66 non-alcoholic) and 215 population controls. Of the alcoholics, 217 had alcohol dependence and 49 had alcohol abuse. Mean ages were: alcoholics, 34.4 yrs (SD = 10.4), non-alcoholics: 33.1 yrs (SD = 12.0).
