Novel P3 amplitude correlated negatively, and novel P3 latency correlated positively, with alcohol use, especially as indexed by high-density drinking. Figure 1 compares grand-average ERPs to novel sounds and grand-average difference ERPs to novel versus standard tones in 2 subgroups (N = 36 individual twins in each) representing the extremes (highest and lowest deciles) of self-reported high-density drinking, MAX-D24. Figure 2 shows the grand-average ERPs to target tones, and Fig. 3 the grand-average ERPs to standard tones in these same 2 groups on N = 36 each.
