we defined for each animal as GCImPFC→BLA / (GCImPFC→BLA + GCIBLA→mPFC), was correlated with discrimination (Figure 6E, r=.50, p<.05), such that stronger evidence for an mPFC lead was present during the CS− compared to the CS+. These findings support a functional role for directionality in the gamma range during fear discrimination, and suggest that safety is associated with a shift towards greater mPFC-to-BLA directionality, similar to our previous findings with theta-frequency synchrony (Likhtik et al., 2014).
