This GWAS was based on individuals in the iPSYCH cohort and compared 2,387 CUD cases (ICD10 F12.1-F12.9) against 1,789 individuals diagnosed with schizophrenia (ICD10 F20) without a CUD diagnosis. QC procedures with respect to individual and genotyping QC were the same as described of the CUD GWAS, and association was calculated using logistic regression, corrected for genotyping wave and PCs from PCA.