increase sIPSC frequency in all CRF1- neurons. Consistent with previous reports by members of this group [51] no EtOH-induced alterations in sIPSC amplitude were observed in either cell population. Finally, retrograde tracing studies revealed that these CRF1-containing neurons project to the BNST. Importantly, superfusion of 44mM EtOH significantly increased the firing rate of all BNST-projecting CeA neurons, regardless of whether these cells were CRF1+ or CRF1−; the authors conclude that EtOH increases the firing rate of all BNST projections originating in the CeA, of which CRF1+ cells are one subtype.
