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Chunk #31 — BACKGROUND — The first ENIGMA‐OCD brain structural connectivity results

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An overview of the first 5 years of the ENIGMA obsessive-compulsive disorder working group: The power of worldwide collaboration.
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small‐worldness (p = .017), and community membership, suggesting lower network segregation. At the regional level, compared to healthy controls, OCD patients showed lower (rank‐transformed) centrality values for caudate and thalamus volume, and surface area of paracentral cortex, suggesting an altered distribution of brain hubs. Centrality, mainly of the cingulate and orbitofrontal areas, was associated with OCD disease duration, indicative of greater involvement of these regions with chronicity.