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Chunk #17 — Method — EEG Data Collection and Reduction

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Resting frontal EEG asymmetry as an endophenotype for depression risk: sex-specific patterns of frontal brain asymmetry.
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summary spectrum for each resting session.2 Total alpha power (8-13 Hz) was then extracted from the spectrum for each resting session and site. An asymmetry score for each resting session for each reference montage was calculated by subtracting the natural log transformed scores (i.e., ln[Right] – ln[Left]) for each homologous left and right pair; e.g., F7 & F8, F5 & F6, F3 & F4, F1 & F2). Higher values on this index putatively reflect relatively greater left activity (i.e., greater right than left alpha; cf. Allen et al., 2004). Asymmetry scores for the two resting sessions within each day were then averaged together to create a measurement of regional brain activity per day. Thus, separate asymmetry scores for four days for each of four reference montages were utilized in analyses, resulting in 16 asymmetry scores per participant at each homologous pair. Although asymmetry scores were computed for all homologous site pairs, analyses for the present study focused on a specific subset of those pairs (F2-F1, F4-F3, F6-F5, F8-F7) that correspond to regions commonly studied throughout the asymmetry literature (pairs F4-F3 and F8-F7; see review by Coan & Allen, 2004) as well as pairs of channels that neighbor these pairs to