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Chunk #29 — Methods — Genome-Wide Association Meta-Analysis (Stage 1) — Choice of phenotypes

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Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.
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WC and WHR were measured in the individual cohorts using standard protocols. Recently a multi-centre comparison of WC measurements at different sites showed that the measurement at different centres have no substantial influence on the association to various adverse health outcomes [32]. In line with this we detect little, if any, heterogeneity at our significant associations, which indicates that it is unlikely that any differences in measurement protocols are having a substantial effect on these (Table S2).