paperKB
coga / coga-kb
Help
Sign in

Chunk #9 — Materials and methods — Procedure — Marijuana administration

Source
Intermediate cannabis dependence phenotypes and the FAAH C385A variant: an exploratory analysis.
Embedded
yes

Text

After cue exposure, participants received a 1-g marijuana cigarette (3.1% Δ9-THC by weight), provided by the National Institute on Drug Abuse and were instructed to smoke it following paced puffing procedures, which produce significant, concentration-dependent increases in psychophysiological and subjective measures (Hart et al. 2001, 2002; Lukas and Orozco 2001). Via audio tape, participants were instructed to “light the cigarette” (30 s), “get ready” (5 s), “inhale” (3 s), “hold smoke in lungs” (5 s), and “exhale.” The interpuff interval was 30 s. Instructions continued until 10 mm of the cigarette remained; participants typically finished the cigarette in 5 m. Participants completed the POMS and BAES 5, 10, 15, 30, and 60 m after smoking, and HR was recorded at these time points.