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Chunk #4 — Methods — Laboratory Measures

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Association of blood lipids with common DNA sequence variants at 19 genetic loci in the multiethnic United States National Health and Nutrition Examination Survey III.
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HDL cholesterol and triglycerides were measured using standard enzymatic methods. LDL cholesterol was calculated using the Friedewald formula with assignment of a missing value for participants with triglycerides exceeding 400 mg/dL. Fasting blood samples were available in 41% of individuals (n=2916), and the remainder were non-fasting. We included both fasting and nonfasting samples in our analyses to increase statistical power.