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Chunk #24 — RESULTS — Results in Female–Female Pairs

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The relationship between genetic influences on alcohol dependence and on patterns of alcohol consumption.
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In our best-fit model, the genetic relationship between our four measures of AC and AD can be assessed in two ways. The most direct measure is the magnitude of the path from the A1 genetic factor to the 4 forms of AC. By this metric, drunk frequency is by a moderate margin the form of AC that best indexes the genetic risk to AD, followed by maximum quantity. An alternative measure is the proportion of genetic risk in the AC measure that is shared with AD. As seen in Table 3, by this index, drunk frequency stands out. Over 90% of the genetic risk for drunk frequency is shared with AD compared to ~70% for the other three measures of AC.