organization of the transcriptome (Lee et al., 2014) and extract some of the subtle expression differences induced by individual neurons and their microenvironments (Lovatt et al., 2014). This and other rapidly advancing computational approaches promise to improve discovery of the functionally relevant molecules and pathways involved in AUD and lead to more targeted treatment approaches, with the potential to integrate changes in gene networks, cell types, and brain regions in the different stages of addiction.
