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Chunk #24 — Materials and Methods — Data Analysis

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A cis-eQTL in OPRM1 is Associated with Subjective Response to Alcohol and Alcohol Use.
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(r2 = 0.03), in relation to a set of phenotypes that were themselves moderately correlated, no corrections for multiple testing were made for any of the described analyses. Analyses conducted with the retrospective self-report measures included participants in both active placebo and alcohol beverage conditions (n = 282), whereas only those individuals assigned to the alcohol beverage condition (n = 152) were retained for analyses of subjective response to alcohol during the alcohol challenge. Means and standard deviations for the above self-report and subjective effects of alcohol measures as a function of rs3778150 genotype are displayed in Table 1.