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Chunk #18 — Statistical analysis

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Genome-wide association studies and the genetic dissection of complex traits.
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The core of the analysis is typically a statistical test conducted for each individual SNP in the array with the objective of selecting those SNPs that exhibit a significant association with the trait. Formally, the procedure consists of testing, for each SNP, the null hypothesis that there is no association between the SNP and the phenotype against the alternative hypothesis that there is an association.