1999; Narushima et al 2003). Patients with right frontal damage, however, are more likely to show signs of inappropriate cheerfulness and mania (Starkstein et al 1989). Further, individuals with affective disorders have shown abnormal laterality patterns that may be suggestive of right hemisphere dysfunction (Jaeger et al 1987; Liotti et al 1991; Phillips et al 2003). There also is evidence of possible premorbid bilateral- and right-frontal abnormalities in individuals at risk for alcoholism, a subset of whom display impulsivity, insensitivity to reinforcement, antisocial personality disorder, etc (Tarter et al 1985; Hesselbrock 1991; Pihl and Peterson 1991; Holdcraft et al 1998; Lappalainen et al 1998).
