the two studies might be due, not only to differing definitions of affecteds, but also the definition of unaffecteds. Finally, the current study did not identify the same SNPs as were noted in our prior study of ANYDEP and its quantitative equivalent in a much smaller subset of these data (N=1,170 – 2,183; Supplemental Table S7), which is not uncommon with the substantially increased sample size used here.