The chromosome 7 locus is located in an intron of FOXP2 (Forkhead box protein P2, index SNP, rs7783012; OR 1·11, 95% CI 1·07–1·15, SE 0·02; p=1·84 × 10−9; figure 1, appendix pp 21–22, 24). The index variant was an eQTL for FOXP2 in brain (prefrontal cortex, anterior cingulate cortex) and adipose tissue, and demonstrated chromatin interactions with FOXP2, MDFIC, and MIR3666 (appendix p 26).
