Our study compared the nicotine inhaler and bupropion versus the combination of the two in a large number of smokers, of which 10% were minority smokers. We observed that minority smokers were less likely to stop smoking at the end of 12 weeks of treatment when compared to white smokers. This is consistent with current US data indicating that overall smoking abstinence rates among white smokers is higher than that of the minority smokers who are trying to quit (Croghan et al. 2008a; U.S. Department of Health and Human Services 1998).