tests of association at imputed SNPs to properly account for the uncertainty that can occur at such SNPs[14]. The results of the simulations are shown in Table 1 and shows that the use of IMPUTE provides a noticeable boost in power over testing just the SNPs on each chip or using Multi Marker tests (as defined in [15]). This agrees with our previous results [14]. It is also very noticeable that imputation reduces the differences in power between the chips and that the use of imputation produces a level of power that is almost as high as our hypothetical ‘complete’ chip.
