Australian adults of European ancestry who completed the Comorbidity and Trauma Study (CATS) and had data on childhood sexual abuse and cannabis use were considered for analyses (N = 1,621). Of these participants, 96.1% reported having ever used cannabis; as such, those who did not report using cannabis were excluded from subsequent analyses, leaving a final N of 1,558 (Table 3). CATS is a case-control study of opioid-dependent individuals (primarily heroin, n = 1,189), aged 18 or older, who were recruited from clinics in the greater Sydney region at which they received opioid substitution therapy (for additional details: Nelson et al., 2013, 2014; Shand, Degenhardt, Slade, & Nelson, 2011) Neighborhood controls (n = 369) who had little or no lifetime history of recreational opioid use were recruited from socially disadvantaged neighborhoods in geographic proximity to locations where cases had been recruited. Participants were excluded for recent suicidal intent and current psychosis. Institutional Review Board (IRB) approval was obtained from University of New South Wales, Washington University School of Medicine, QIMR Berghofer Medical Research Institute, and Sydney area health service ethics committees.