Gene groups were analyzed by hypergeometric statistical methods using the Database for Annotation, Visualization and Integrated Discovery v6.7 software.35 DAVID parameters used the recommended Gene Ontology categories (GOTERM_BP_FAT, GOTERM_CC_FAT, and GOTERM_MF_FAT) with “high” classification stringency to ensure a strong association between genes. An additional pathway analysis investigated if there were differences in gene ontology depending on CNV type. Three CNV categories were defined: A, B, and C (Figure S2, available online).
