determine which criteria or items yield incremental validity when the best performing ones have been entered into prediction models. While some validity data are available on relations of individual DSM criteria with cessation outcomes or smoking heaviness measures [26, 35], such relations do not reveal which criteria may contribute to validity in the context of other valid criteria. It is also vital to examine the relation of new criteria with additional TD outcomes: treatment outcomes and contribution to treatment algorithms, sensitivity to critical gene variants, work for nicotine/tobacco in instrumental self-administration paradigms, and so on.
