Phenotypic assessments using these instruments were conducted by a team of 11 psychiatric nurses with an average of greater than 12 years of hospital-based (in Chiang Mai), psychiatric experience under the longstanding clinical supervision and training of a third Thai study physician (KS). Interviewers had prior experience with the Thai MINI, but underwent additional specialized training in the modified lifetime version, as well as full formal training in the relevant sections of the Thai SSADDA (conducted by RK, RM and JG). Subsequent to training, and as part of a process of formal certification prior to the study, each nurse clinician conducted a series of 10 patient assessments (8 training and 2 certification) of established clinical cases (diagnosed by a senior psychiatrist, KS), consisting of non-study subjects with and without OD. All training interviews were reviewed individually for procedural accuracy by a SSADDA-certified Thai study physician (RK) and results of training interviews were reviewed as a group with all 11 nurse clinicians, Thai study physicians (RK and KS), and U.S. investigators (RM and JG). Completion of the initial training course, 8
