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Chunk #24 — DISCUSSION

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Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families.
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with increased risk for childhood adversities which themselves are associated with earlier sexual debut (61). Separated parents, like parents with AUDs, may provide less monitoring of their children, so that opportunities for substance use and risky sex are more plentiful. Parental separation may be a marker indexing a broad risk that includes lax parental monitoring as well as potentially greater genetic liability to substance use, since parents with AUD are more likely than parents without to separate (15, 16), and parental AUD is associated with increased genetic risk for other substance use in offspring (58).