As depicted in Figure 2A, buprenorphine treatment days were associated with lower odds of hospitalization or ED visit for acute drug-related poisonings among individuals with cooccurring SUD (odds ratio [OR], 0.56 [95% CI, 0.48-0.65]) and those without cooccurring SUD (OR, 0.57 [95% CI, 0.53-0.63]). Comparable protective associations were observed in association with ER naltrexone treatment days for individuals with cooccurring SUD (OR, 0.44 [95% CI, 0.30-0.63]) but not for individuals without cooccurring SUD. No protective association was observed for oral naltrexone.
