split between different classes of actively repressed or inactive, quiescent chromatin. We found that the CTCF-binding associated state is relatively invariant across cell types, with individual regions frequently occupying the CTCF state across all six cell types (Figure 5C). Conversely, the E and T states have substantial cell-specific behaviour, whereas the TSS state has a bimodal behaviour with similar numbers of cell-invariant and cell-specific occurrences. It is important to note that the consensus summary classes do not capture all the detail discovered in the individual segmentations containing more states.