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Chunk #28 — How to best define an SUD phenotype

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Recent advances in the genetic epidemiology and molecular genetics of substance use disorders.
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Application of these methods to large epidemiological databases suggests that substance abuse and dependence are not separate disorders, nor are symptoms of abuse ‘milder’ than those of dependence. Instead, an emerging consensus for most illicit substances is that the diagnostic criteria for abuse and dependence—previously considered to be different manifestations of SUDs—actually measures a single underlying dimension of liability.