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Chunk #26 — Results — Association with psychiatric and substance use disorders

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The variance shared across forms of childhood trauma is strongly associated with liability for psychiatric and substance use disorders.
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Across all three samples, CTF scores were associated with significant risk for lifetime individual licit and illicit substance dependence diagnoses, conduct disorder, depression, PTSD, and suicide attempt (Table 3). Examinations focusing on the numbers of licit and illicit drug dependence diagnoses found consistent evidence (Table 4) that CTF scores are also associated with incrementally greater magnitude of risk for larger total numbers of diagnoses. The CTF is thus a unitary measure with strong psychometric properties that captures covariance common to three types of adversity and is associated with significant risk of psychiatric and substance use disorders indicative of its strong predictive validity.