may not be readily generalizable to other populations. Nonetheless, datasets enriched for specific clinical outcomes, such as the COGA data enriched for AUD, provide an excellent opportunity for identifying markers and predictors of these outcomes of interest. However, replication studies using other data from community samples are needed to confirm these findings in the general population. Details on the screening and selection of participants for the current study are described in the Supplemental Materials (see Section S1.1 Sample Description and Figure S1 in the Supplementary Materials). During assessment, the memory and control groups were also matched for age, sex, self-reported race, genetic ancestry, and the following alcohol use patterns assessed by their last SSAGA interview conducted ~18 years prior to the recent telephone interview (see Table 1): (i) continued high-risk drinking (men with 5+ drinks/day or 15+ drinks/week and women with 4+ drinks/day or 8+ drinks/week) and meeting the criteria for DSM-5 AUD diagnosis derived from SSAGA items (N = 68/group), (ii) low-risk drinking (fewer than 5 drinks/day for men and 4 drinks/day for women) without meeting the criteria for AUD diagnosis (N = 9/group), and (iii) abstinence from drinking (N = 17/group).
