Overall, the implications of poor cognitive function are far reaching. Research suggests that MDD patients with neuropsychological deficits tend to be less compliant with antidepressant treatment (35) and show an increased risk for suicide (36), both of which highlight the clinical importance of neuropsychological deficits in depression. In addition to these clinically relevant cognitive deficits in MDD, other cognitive dimensions of depression, such as emotion processing and social cognitive functioning, can be delineated. These dimensions have long been considered at the core of depressive symptoms, as they can affect not only how patients feel about themselves and others but also how they function on a daily basis and at work. Emotional processing distortions in MDD, namely negative attention bias to sad facial expressions (37) and oversensitivity to negative feedback (38), are key clinical features of depression, which may be present in acute and remitted MDD. Similarly, social cognition, which is the ability to identify, perceive, and interpret socially relevant information in relation to oneself and to others, is an important skill that plays a significant role in successful interpersonal and
